The concomitant use of opioids with other medicine that have an effect on the serotonergic neurotransmitter method has resulted in serotonin syndrome.
Promethazine with Codeine Oral Resolution contains promethazine, a phenothiazine. Phenothiazines are connected with dystonic reactions, significantly in pediatric people who may have an acute ailment involved with dehydration.
Recall, maintain this and all other medicines out of your attain of youngsters, never ever share your medicines with Other people, and use this medication only for the indicator prescribed.
Prevent the use of Promethazine with Codeine Oral Answer in patients with head harm, intracranial lesions, or maybe a pre-current increase in intracranial stress. In sufferers who could possibly be prone to the intracranial consequences of CO two retention (eg., Those people with evidence of elevated intracranial tension or brain tumors), Promethazine with Codeine Oral Solution may perhaps cut down respiratory push, and also the resultant CO 2 retention can even further increase intracranial strain.
Ailments OF USE: The knowledge During this databases is intended to health supplement, not substitute for, the skills and judgment of healthcare professionals. The data isn't intended to go over all probable works by using, Instructions, safeguards, drug interactions or adverse effects, nor need to it's construed to indicate that usage of a specific drug is Harmless, appropriate or powerful for you or any person else.
For anyone who is prescribed this medication on a daily schedule and miss a dose, take it when you try to remember. Whether it is near the time of the subsequent dose, skip the missed dose. Acquire your following dose in the regular time. Will not double the dose to catch up.
Make certain that individuals have an oral dosing dispenser that steps the suitable quantity in milliliters. Counsel sufferers on how to benefit from an oral dosing dispenser and correctly evaluate the oral suspension as prescribed.
To help stop withdrawal, your doctor may perhaps decreased your dose little by little. Withdrawal is more very likely When you have utilised this medication for years (various weeks) or in large doses. Tell your doctor or pharmacist right away For those who have withdrawal.
Go through the Medication Tutorial supplied by your pharmacist before you start taking promethazine/phenylephrine/codeine and each time you obtain a refill. If you have any inquiries, inquire your medical doctor or pharmacist.
Psychological dependence, Actual physical dependence, and tolerance may perhaps produce upon recurring administration of opioids; as a result, Promethazine with Codeine Oral Alternative must be prescribed and administered for the shortest length that may be steady with individual individual procedure objectives and clients should be reevaluated just before refills [see Dosage and Administration (2.
This solution may click here well contain inactive components, that may result in allergic reactions or other complications. Check with your pharmacist For additional specifics.
Get this medication accurately as prescribed to reduced the potential risk of addiction. Question your doctor or pharmacist for more information.
Hemodialysis is not routinely applied to reinforce the elimination of codeine or promethazine from the body.
Promethazine is metabolized with the liver to many different inactive metabolites like sulfoxides of promethazine, N-demethylpromethazine and other glucuronides.